Burke worked as a model for Venus Swimwear and Frederick's of Hollywood. From 1999 to 2002, Burke became known while hosting Wild On!, a travel series on the E! Entertainment Television channel replacing previous host Jules Asner. As part of the series, she traveled the world extensively, profiling many popular travel destinations.
Burke first appeared nude during her early modeling career for the website BlueNudes, and most notably after gaining fame in the May 2001 and November 2004 issues of Playboy. She also appeared in men's magazines such as Maxim, Stuff, and FHM. In 2007, she was listed as one of Blender's hottest women of film and TV.
